A Hannibal couple was arrested Thursday during a police search of their home at 810 Hayward.
William "Billy" Motley, 43, and Deanna Motley, 44, were both charged with attempt to manufacture a controlled substance.
The Northeast Missouri Narcotics Task Force, the Marion County Sheriff's Department and the Missouri State Highway Patrol executed a search warrant at the Hannibal home.
Police say methamphetamine, items used in the manufacture of methamphetamine, drug paraphernalia, heroin and marijuana were seized in the search.
Associate Circuit Judge John Jackson issued the arrest warrant for Billy and Deanna and set the cash only bond of $100,000, according to the Northeast Missouri Narcotics Task Force.
The couple remains lodged in the Marion County jail.