Easing bone marrow transplants to widen their use

Scientists are seeking a new approach in the use of bone marrow transplants as the procedure undergoes a quiet revolution.

No longer just for cancer, research is under way to ease the risks so they can target more people with diseases from sickle cell to deadly metabolic disorders.

Scientists also want to learn if such transplants can be used without having to deplete the recipient's own marrow supply first. If that succeeds, bone marrow can eventually be used to treat a variety of diseases - and ultimately marrow transplants can be used even when donors aren't a good genetic match.