The rough night of storms led Gov. Jay Nixon to declare a state of emergency. Nixon's office issued the declaration late Friday after the storms that spawned tornadoes, damaging winds and heavy rain crossed Missouri from the southwest to the northeast.
The St. Louis area took the brunt of the storms, with widespread power outages and structural damage.
There were reports of a tornado cited near St. Charles on Friday night, along with reports of home damage. It wasn't immediately clear if anyone was hurt. The National Weather Service reported several downed trees. Parts of the region also had hail. Rainfall was heavy, prompting flash flood concerns.
Forecasters posted numerous tornado warnings beginning around 6:30 p.m. Friday in eastern Missouri. At least one tornado touched down in Montgomery County , about 70 miles west of St. Louis, but emergency manager Bob Bishop said there were no injuries.
The State Emergency Operations Center has been monitoring the storm system throughout the week as several days of heavy rain pushed rivers and streams out of their banks and caused massive flash flooding.
The St. Louis Cardinals' game with the San Francisco Giants was canceled nearly 30 minutes before the severe weather was expected to arrive downtown.